Gabrielsen, Mari; Ravna, aina westrheim; Kristiansen, kurt; Sylte, Ingebrigt (Journal article; Tidsskriftartikkel; Peer reviewed, 2011-06-14)
The serotonin (5-HT) transporter (SERT) plays
an important role in the termination of 5-HT-mediated
neurotransmission by transporting 5-HT away from the
synaptic cleft and into the presynaptic neuron. In addition,
SERT is the main target for antidepressant drugs, including
the selective serotonin reuptake inhibitors (SSRIs). The
three-dimensional (3D) structure of SERT has not yet been
determined, ...